Prevention

Diet
Plant-based foods, e.g. tomatoes and carrots (sources of carotenoids); whole grains, seeds, pulses, beans and soya products (sources of phytoestrogens) likely protection with fibre, fish, poultry, olive oil likely protection with vitamins A, C, D and E possible protection with calcium
Avoid being overweight
Regular exercise
Avoid smoking
Avoid long-term use of hormone replacement therapy
Control occupational exposure, e.g. to asbestos, diesel and gasoline exhaust,solvents, herbicide.

Strategies available for women at very high-risk of ovarian cancer
Annual screening with transvaginal ultrasound with Doppler colour measurements and CA125, commencing at 35 years or at least 5 years earlier than the age at diagnosis of the youngest ovarian cancer case in the family.

For women shown by genetic testing to carry a high-risk mutation, consideration should be given to prophylactic surgery such as bilateral salpingo-oophorectomy
Consideration of possible increased risk of breast cancer:

(a) monthly breast self-examination; (b) clinical breast examination every 6 months; (c) advice to report any breast changes immediately; (d) annual mammographic screening with ultrasound from the age of 30 years or at least 5 years earlier than the age at diagnosis of the youngest breast cancer case in the family; (e) consideration to prophylactic mastectomy in women found to carry a high risk mutation.

Participation in clinical trials of screening and chemoprevention

Avoid long-term use of hormone replacement therapy