Etiology
A dysfunction at any level of Hypothalamus-Pituitary-Ovary-Uterus Axis can result into amenorrhea. Amenorrhea can be due to:
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Hypothalamic dysfunction
Anorexia(secondary amenorrhea)
Obesity(secondary amenorrhea)
Vigorous exercises (secondary amenorrhea)
Excess cortisol, androgens, and prolactin (primary amenorrhea)
Brain malignancy(secondary amenorrhea)
Pituitary dysfunction
Pituitary tumors(secondary amenorrhea)
Hyperprolactinemia(secondary amenorrhea)
Pituitary infarction(secondary amenorrhea)
Sheehan’s syndrome(secondary amenorrhea)
Ovarian dysfunction
Menopause(secondary amenorrhea)
Polycystic ovarian syndrome (secondary amenorrhea)
premature ovarian failure(secondary amenorrhea)
Autoimmune ovarian destruction(secondary amenorrhea)
Ovarian Irradiation(secondary amenorrhea)
chemotherapy(secondary amenorrhea)
Endometriosis(secondary amenorrhea)
Turner syndrome (primary amenorrhea)
End-organ dysfunction
Imperforate hymen (primary amenorrhea)
Endometrial scarring (secondary amenorrhea)
Asherman syndrome (secondary amenorrhea)
Other causes
Pregnancy (The most common cause of secondary amenorrhea)