In case of intact ectopic pregnancy,
methotrexate (IV) 50mg/M2 single dose
OR
methotrexate 2.5mg (PO) 24hourly for 5days (in case IV methotrexate is not available)
Perform weekly pelvic ultrasound to ensure regression of Gestation sac
Contraindications of methotrexate include a ruptured ectopic pregnancy, ectopic mass greater than 3.5 cm,presence of fetal cardiac activity, high level hCG value (10,000 IU), breastfeeding and immunodeficiency.
In case of ruptured ectopic pregnancy:
IV fluids based on the amount of blood lost
Blood transfusion if indicated depending on the blood loss
Perform Emergency explorative laparotomy.
